Portal TOL Technology On-Line

Meta-Search TOL [e-books, codes, sites]:
tutorials, softwares, games, videos, projects, categories, articles, links (and images)*

- shortcuts for keywords, websites, videos, products of :
Lecture by Dr Ranjana Arya JNU


Lecture by Dr. Ranjana Arya (JNU)


Description: Dr. Ranjana Arya is an Assistant Professor at the School of Biotechnology at Jawaharlal Nehru University (JNU), New Delhi.

Distal myopathy with rimmed vacuoles (DMRV) or hereditary inclusion body myopathy (HIBM) is an autosomal recessive myopathy with progressive muscle disorders and is pathologically characterized by formation of numerous autophagosomes called rimmed vacuoles. HIBM has been identified in Indian patients with compound and heterozygous genotype. DMRV/HIBM usually starts to affect adults from 15 years of age upto 40 years, with an average onset of 26 years and with an initial symptom of altered gait. However, the precise mechanism that leads to the formation of rimmed vacuoles has remained elusive. DMRV/HIBM is caused by mutations in the UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) gene which encodes a bifunctional enzyme that catalyzes the rate-limiting step in sialic acid biosynthesis. The status of sialylation in wild type vs mutant GNE cell lines is not clear. In the laboratory, we are interested to study the effect of various GNE mutations on sialylation of proteins and formation of rimmed vacuoles in mammalian cells. This would provide insights into many biological processes such as cell adhesion and signal transduction which is associated with sialylation of glycoproteins and glycolipids.

Sent by: Genomics of Rare Diseases India Alliance Network
( including the playlists )

Published at: 2015-02-27 22:13:10.000
Total of views: 786 - Duration: 53M21S

- Favorites: 0 - Likes: 8 - Dislikes: 1
Total of comments: 1 - Category id: 28

In window : C8pY_K7O3ok
(Shockwave Flash Object)

¬ Video hosted by Youtube : the portal TOL is not responsible for this type of content

- requests for removal of this video based in laws like the DMCA must be sent to Google

Click this code to Select and Copy instantly
( Ctrl-C is necessary in the Firefox or Chrome )

Video HTML5 / Flash widescreen

Space destined for new content such as Comments, Updates, Suggestions, Constructive Criticism, Questions and Answers about "Lecture by Dr Ranjana Arya JNU", doubts and solutions that help other visitors, users, students, professionals, etc.

| be the first ( soon ) to send a feedback related to: Lecture by Dr Ranjana Arya JNU |

Important ( before send a comment ) : Don't use this space to send another requests as content removals, claims, complaints, or to warn about errors that occurred on this page. Please, [click here] to report these or any other kind of problem for Lecture by Dr Ranjana Arya JNU, even if it is temporary error or in the server...

Part of this page can be based on free documentation and paid or open content, including multimedia, therefore specific requests should be sent to the external source, the site Videos.Portal-TOL.net is not responsible for its edition and any page refresh can be made immediately or in a short and long term periods, depending on the origin.

Articles starting with the char L :

Related websites with Lecture by Dr Ranjana Arya JNU *

 Keywords/tags :   #Arya   #Dr   #JNU   #Lecture   #Ranjana   #by  

( go to the back page | top of this page )

© Portal T.O.L. Technology On-Line powered by TOL framework

[ Tutorial On-Line changed the name to Technology On-Line when completed 15 years ]
Portal-TOL.net Technology On-Line Portal.TOL.pro.br